Food toxicology degree is an important degree course for the specialty of food quality and safety, food science and related to food safety as the premise, is a theoretical courses and teaching and experiment technology. In recent years, due to the increase in each discipline development and curriculum, curriculum is to represent the general trend for shorter periods, food toxicology course in some universities hours only 20 hours or so, the existing materials can not adapt to the change of teaching work, bring bigger difficulty to teaching. The book notice food toxicology foundation, system, application and progress in contents, relationship better handle the basic and advanced, the traditional and current situation. Based on the related subject systematically introduces the basic concepts and methods, food toxicology of the latest technology to food toxicology, make a written for food quality and safety of students, is also suitable for engaging in food science, food engineering, food processing, food inspection, health inspection, foreign trade commodity inspection, animal (water) related work products processing, veterinary health inspection and preventive medicine, need some basic knowledge of toxicology of readers, but also as agriculture, light industry, biological, medical and health, environmental protection and other related research, researchers in disciplines direction, professional and technical workers and health food supervision and management personnel reference book. The book written in young and middle-aged teachers who are Food Science College of Jiangnan University with a doctoral degree, rich experience in teaching and research in this field is. Each chapter is written as follows: Division of Sun Zhen, chapter one (Introduction), the second chapter, the seventh chapter, the twelfth chapter (experimental), appendix; Sun Jin, the third chapter, the eighth chapter, the ninth chapter; Sun Xiulan, chapter tenth, chapter eleventh; King Zhou Ping, the fifth chapter, the sixth chapter; Yang Jingqiu (Master), fourth chapter. Finally, by Sun Zhentong. Limited to writing staff knowledge and writing ability, and the writing time, inevitably.In many deficiencies, urge readers to put forward valuable opinions and suggestions, so that we in the future to correct and improve the.
The book is divided into twelve chapters, systematically introduces the basic concept, development of toxicology, xenobiotics in vivo absorption, distribution, excretion, transformation and the basic knowledge of xenobiotics in vivo process and research methods; the combined effect of various toxic effects and their influence factors of the effect of host and environment and poison; mechanism of poison toxic for organism; describes general toxicity, carcinogenesis, developmental toxicity and teratogenicity and evaluation methods of chemicals; and introduces the concept and process of risk assessment, safety evaluation; the book also with some progress in theory and practice in recent years the toxicity of the new technology are introduced in toxicology research. In addition, the book also introduced the main experimental food toxicology, the appendix lists common important toxicological calculating table. This book is designed for the preparation of food quality and safety of students, is also suitable for engaging in food science, food engineering, food processing, food inspection, health inspection, commodity inspection, foreign trade of livestock (water) related work products processing, veterinary health inspection and preventive medicine, need some basic knowledge of Toxicology of readers agriculture, light industry, but also as, biological, medical and health, environmental protection and other disciplines, the direction of the research staff, professional and technical workers and food supervision and inspection and management of reference books.
The first chapter first day toxicology overview, food toxicology concept two, food toxicology task three, toxicology research field second day toxicology, toxicology development history of the origin and development of two, our country food toxicology development section third food toxicology research method, chemical method, biological method in section fourth, food two toxicological principles and limitations, food toxicology experiment principle two, food toxicology experimental limitations in section fifth, the tendency of the development of food toxicology, food toxicology experiment trend, the development trend of the two century toxicology three, experimental animal from a single model to feature model development questions for review second chapter the basic concepts of toxicology the first section poison, toxicity and toxicity of toxicants and poisoning, two, toxicity, hazard, safety three, toxicity and type four, damage and non - damage effects of five, six, the target organ toxicity profile seven, biomarker second dose, dose response relationship (matter), dose the amount of reaction and reaction, two, dose response relationship (matter) three, dose response relation curve of the third section of the table Commonly used parameters and toxicity, a lethal dose two, minimal effect level three, no effect dose four, poisoning safety risk indicators fourth day limit, a daily intake of two, the maximum allowable residue three, reference dose (concentration), four benchmark dose questions for review third chapter chemicals biological transport the first section provides an overview of the second section of biological transport and biological membrane, membrane two, passive absorption three, special transport four, film transport section third absorption, absorbed via the gastrointestinal tract two, absorbed through the respiratory tract, skin absorption of three by fourth section cloth, the basic concept of distribution, two xenobiotic organs three, the distribution of xenobiotics in the distribution process barriers four, xenobiotics in the organization of the storage section fifth discharge, through the kidney with urine excretion by the liver, two with biliary excretion by three, lung with exhaled excretion of four, other way from questions for review fourth chapter xenobiotic biotransformation the first section outlines a, biotransformation of step two, biotransformation meaning second Ⅰ phase reaction of enzyme, oxidation enzyme system two, third phase Ⅰ anti hydrolase Should a, oxidation reduction reaction of three, two, hydrolysis reaction...... The tenth chapter ninth chapter application specific toxicity test in vitro and the new technology of xenobiotic toxicity mechanism the sixth chapter of fifth chapter of exogenous chemicals poisoning factors seventh chapter general toxicity and evaluation methods of chapter eighth chemicals in toxicology safety evaluation of food in our country the eleventh chapter in common food toxic substances in Chapter twelfth the appendix references
Illustration: two, food toxicology task food toxicology is a subject of potential hazards and its action mechanism on human health or the presence of toxic, harmful substances may be mixed with the study of food toxicology methods, including acute and long-term effects of foodborne disease is chronic foodborne hazards. Relates to all links from food production, processing, transportation, storage and sale of the entire process, the food production of industrialization and new technology, and new understanding of harmful factors in food. The study of xenobiotics, including material industrial products and industrial use of raw materials, food additives, pesticide, pigment and traditional, and recently appeared in two (evil) dioxin pollution, chloropropanol, acrylamide, mad cow disease, veterinary drugs (including hormone) toxicological issues residues, mycotoxins contamination etc. the new. In the process of food, sometimes can form a variety of pollutants, such as Roasted Duck and mutton cubes roasted on a skewer can produce some carcinogens and mutagens (such as polycyclic aromatic hydrocarbons and heterocyclic amine); can produce carcinogenic bacon, salted fish and pickled vegetables (such as nitrosamines). In addition, it must also be pointed out is required for maintaining normal human physiological nutrients, such as vitamins, trace elements, and even excessive intake of fat, protein and sugar, can also cause some side effects, especially some trace elements, such as zinc, selenium, manganese etc.. Therefore, in the field of food toxicology of xenobiotics and at the same time, also should study the essential nutrients intake of excessive toxicity caused by. Food toxicology function is from the aspect of toxicology, the toxic mechanism of exogenous chemicals may contain study in food for human consumption, test and evaluation of food (including food additives) safety or security range, so as to ensure the health of human objective.
"Concise food toxicology:" higher education "eleven five" planning materials
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