Clinical pharmacology

Date of publication:2004-9   Press: Higher Education Press   Author:Wang Huailiang   Pages´╝Ü461  
Preface

Illustration:
Summary

Remember in more than 10 years ago, I do breathing professional professor in former West China Medical University, often lectures over, I think of this problem: education is carrying the burden of responsibility, how? When I went to the leadership post, from the initial medical university Vice Chancellor, the provincial health department director, Vice Minister of the Ministry of health, to the present Chinese Doctor Association, although never in charge of the teaching work, but the problem is often haunt me, thinking has never stopped, even today, the answer is becoming increasingly clear, clear! It is to develop education, to progress, the first education idea must undergo profound changes, the connotation of education must be greatly extended, we must reform the teaching mode. Specific to the medical education, there are a few points: my personal views on Teaching: first, medicine is related to the life, health science, must emphasize rigor; second, medicine is a borderline science, and is developing very fast, it should be stressed that teachers continuously updated knowledge, ability and accept new knowledge, new theory the students, meet the demand of knowledge; third, the medical work in addition to mend his ways to save him, also involves a series of problems of ethics, moral, legal, medical education should increase the number of social science knowledge, and strengthening the training of medical students humanistic concern spirit; fourth, the medical profession more morphological courses, learning need to memorize the hard back but in practice, emphasizes the flexibility. Therefore, attention to the cultivation of image thinking and logical thinking of students, that is usually what we call the clinical thinking ability, especially important. In the text: first, the content in the emphasis on "three basic" at the same time, should be able to reflect the development and change of disease spectrum and discipline; second, pay attention to content in science at the same time, should be for the sake of teaches and scholars, is complicated, profound knowledge, represented by text or graphics simple; third, teaching materials should fully reflect the characteristics of medical of this discipline, that is, the content of many morphological method. Therefore, should do with pictures, and even some contents of available video to express. Although he has some ideas of teaching and teaching material construction, but the higher education press asked me to order this set of medical materials, made me very embarrassed. One is I leave education, many years of clinical work; two is previously I invited to many other experts to do the order or sequence to a lot, the authors do not would favour one more than another suspected. But I read the materials planning and part of the chapter, a bright eyes, can not help but let go. This set of teaching materials have many novel in the content, form 1 Basic Disciplines: materials that combine the theory and clinical, cut to make the subject system and give simple and complex content, highlighting the characteristics of clinical services, lay the foundation; 2 clinical teaching materials according to the changes of disease spectrum in recent years the emphasis, introduces the common disease in clinic, medical knowledge, technology, and increase in recent years is recognized, mature new knowledge, new technology; 3 this is the three-dimensional teaching material, a set of real significance not only illustrated, with students and teachers teaching multimedia CD-ROM CD-ROM. CD rich in content, there are a large number of pictures, the medical record analysis, advances in lectures, exercises. Greatly enriches the content of teaching materials, to medical education should be based on visual teaching objective; 4 this textbook author team of younger, with an average age of 50 years old. For the returned personnel as the backbone, and active in teaching, clinical a gleam of.
Catalogue of books

The first clinical pharmacology introduction the first chapter first development of clinical pharmacology in Second Clinical Pharmacology subject task, teaching and training in two, clinical research and evaluation of three, the market re evaluation of four drugs, adverse drug reaction monitoring five, clinical pharmacological service six, technology and consulting services section third clinical pharmacology research content, safety studies, two clinical pharmacokinetic studies, three Clinical Pharmacodynamics Study Section fourth therapeutics, therapeutics content two, drug treatment principle fifth section of clinical pharmacology and therapeutics of learning methods. The second chapter pharmacodynamics of drugs effect and effect of second drugs the dose effect relationship of a quantity of dose-response curves, two, mass curve of dose-response relationship with third day aging aging Qu Xiandi four mechanisms of drug action, drug physicochemical mechanism two, supplement the body lack of various material three, effects of endogenous neurotransmitter and hormone four, act on specific target the fifth section receptor theory and its clinical significance, the definition and characteristics of a receptor, receptor theory three two The classification of drugs, four, receptor type five, regulation of receptor six, receptor related diseases seven, receptor and clinical section sixth influence factors of drug a, body factors, drug factors two chapter third clinical pharmacokinetics of drugs in vivo process and its influence factors, absorption two, three, four, second section of biotransformation excretion pharmacokinetics basic principle and parameter calculation, pharmacokinetics principle two, pharmacokinetic parameters and basic calculation method of section third of population pharmacokinetics, drug metabolism and pharmacokinetics of a group of two, the basic concept of population pharmacokinetics in clinical application of fourth disease on the pharmacokinetics of the drug metabolism and pharmacokinetics, liver disease, kidney disease, the effects of two on the pharmacokinetics of three, congestive heart failure on the pharmacokinetics of the fourth chapter of drug metabolism and clinical rational use of drug metabolizing enzymes, the first section of an oxidative metabolism enzymes, oxidation of CYPlA2 two metabolic enzyme CYP2C9 three, CYP2C19 four, oxidative metabolism enzymes oxygen generation Xie Mei CYP2D6 five, CYP3A4 six, oxidative metabolism enzymes esterase seven, UDP- glucuronic acid transferase eight, N- acetyl transferase nine, glutathione S- transferase second factors affecting drug metabolism and its clinical significance, CYP450 induction and inhibition of liver function injury in three, two, four, first pass metabolism active metabolite, before five medicine six, seven neonatal drug metabolism, drug metabolism effect of diet on the fifth chapter of new drug research and clinical trials of new drug research, first a new concept and classification of drug discovery approaches two, three, four, Chinese herbal medicine research and ideas for future drug research mode five, course of development of new drugs for clinical trials, second section of a new drug clinical trials two basic requirements, new drug clinical trial principle three, clinical trials, relevant provisions of section third of new drug evaluation, evaluation of two new drugs a pharmacy, drug evaluation, three new drugs listed after the evaluation of new drugs and drug administration, the sixth chapter first new drug application and review, a drug registration and new drug application two, new drug approval process and technology second sections of clinical research on new drugs of drug management, drug management two, monitoring period, new drug management three Technology transfer third day our drug management regulations and safety evaluation standard, China's drug control laws and mechanism of two, our drug safety evaluation standard fourth day drug management, the national essential drugs two, prescription and non prescription drugs three, special drug management chapter seventh first quarter pharmacogenetics pharmacogenetics and drug metabolism and pharmacokinetics and pharmacodynamic relationship, pharmacogenetics of definition two, pharmacogenetics and drug metabolism and pharmacokinetics and pharmacodynamics. In the second part the tumor chemotherapy pharmacogenetics, mercaptopurine, a two fluorouracil third antipsychotic pharmacogenetic a, tardive dyskinesia, two psychiatric medication fourth cardiovascular disease treatment of a cardiovascular disease pharmacogenetics pharmacogenetics, two, cardiovascular drug metabolism of pharmacogenetics chapter eighth drug negative reactions and drug-induced diseases section of adverse drug reactions, adverse drug reaction concept two, adverse drug reaction type three, adverse drug reactions constitute four, adverse drug reaction mechanism of five, adverse drug reaction monitoring section second medicine source disease, drug-induced Allergy in two, other common drug-induced diseases in three, drug-induced disease diagnosis and treatment principle of the ninth chapter of drug abuse and drug dependence of the first section of drug abuse, drug abuse, a concept two, the harm of drug abuse in section second, drug dependence, drug dependence, definition two dependent drug classification section third spirit active substance toxicology section fourth common drugs, opioids, cocaine, marijuana, two three, five four sedative hypnotics, amphetamine type six, type seven, fifth section of hallucinogens ethanol detoxification, detoxification of drugs for the treatment of a period of two, preventing recurrence of drugs for the treatment of drug abuse control section sixth, international drug the abuse of regulation two, China's drug abuse control chapter tenth drug interactions in section one, the type of drug interaction two, adverse drug interactions prevent second drug interaction mechanism...... Clinical application of treatment of fourth @##@ endocrine and visceral disease treatment third cardiovascular and blood disease in eleventh chapter to seniors' drug clinical pharmacology chapter twelfth perinatal pharmacology second articles of nervous and mental disease of drug treatment of fifth infectious diseases and the treatment of malignant tumors of sixth biological products "Clinical pharmacology Clinical Pharmacology" by the China Medical University doctoral tutor Professor Wang Huailiang, the famous professor from Peking Union Medical College, Peking University, Fudan University, Central South University, Shandong University, Jilin University, Xi'an Jiao Tong University, Medical University Of Tianjin, Harbin Medical University, Shenyang Pharmaceutical University, Dalian Medical University, Second Military Medical University, Third Military Medical University, China Medical University and other well-known medical institutions of scientific research, has participated in the preparation of experienced teaching. There are 16 doctoral tutor editor. "Clinical Pharmacology" as a medical plan of national universities materials, in clinical medicine, the baseBasic medical, prevention, nursing, pharmacy, dental, forensic and other professional undergraduate training objectives as the preparation of guidelines, but also the national licensed pharmacist examination of practicing physicians, syllabus. "Clinical Pharmacology" on the "Three Basics", "three strict '' basis, pay attention to scientific sex, advanced sex, enlightening, practicality, applicability and novelty; according to the needs of clinical medicine, systematic and concise introduction to the basic theory and application of clinical pharmacology, novel content, reflects the progress of modern clinical pharmacology. "Clinical Pharmacology" is divided into 6 parts and 36 chapters. The first section, this paper introduces the basic theory of clinical pharmacology. Second to sixth for the theory, in addition to drug introduction of nervous and mental, endocrine, cardiovascular, blood, liver disease, the treatment of infectious diseases, but also according to the change of the disease spectrum, is a special chapter introduces cerebrovascular disease, dementia, diabetes, liver disease, migraine, pulmonary hypertension, sexual dysfunction, AIDS drug treatment etc.. The main content involves the field of clinical pharmacology and therapeutics, is of great value to guide the rational use of drugs. "Clinical Pharmacology" the beginning of each chapter are the key content that, for students to master learning focus. To tie in with the bilingual teaching, at the end of each chapter are given English abstract. "Clinical Pharmacology" suitable for university clinical medicine, basic medicine, prevention, nursing, pharmacy, dental, forensic and other professional undergraduate and seven year students use, can also be used as a reference book for medical, pharmaceutical, forensic postgraduates and other professionals, and continuing medical education.
Chapter excerpt

Construction of Higher Education Press of medical materials, by the National Higher Education Research Association, will China medicine handsome and our ten famous medical colleges common in early 2002 launched, planning, and then there are dozens of colleges to join. This teaching material construction a total of nearly two thousand authors to write, have not only the medical circles, academician of Chinese Academy of engineering, medical professional committee leadership and academic backbone in them, the more gratifying is also absorbed a large number of in the teaching, clinical front-line teachers. "Higher Education Edition" medical textbooks in addition to keep domestic textbooks has "Three Basics" knowledge, change with the transformation of medical model, disease spectrum, delete the old theory, content, add new knowledge, new technology is recognized by the. And in order to display three-dimensional, serialized form for the majority of teachers and students, fully embody the characteristics of medical education. I clubs in recent years, in addition to being published, other professional level of medical materials, will be the construction of teaching resources storehouse, the corresponding subject website, in order to provide three-dimensional teaching system, teaching the teaching purpose solution. The pursuit of educational philosophy, advanced teaching methods, the construction of excellent teaching material, it is our common desire!
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